Lauren Saunders

Postdoctoral Fellow
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lsaund11obfuscate@uw.edu

Lauren Saunders was a postdoctoral fellow in the Trapnell lab. She is interested in the transcriptional programs that drive cell lineage specification during embryonic and post-embryonic development. She completed her PhD at the University of Washington with David Parichy and Cole Trapnell where she studied how thyroid hormone, a common endocrine signal, coordinates neural crest derived lineages during post-embryonic development in zebrafish. She received a B.A. in Biology from St. Olaf College. And before starting graduate school, I studied blood vessel development and morphogenesis in Dr. Victoria Bautch’s lab at UNC-Chapel Hill.

Lauren accepted a position as a tenure track junior professor at the Center for Organismal Studies at Heidelberg University. Her lab will be opening in January 2024!

Papers

Embryo-scale reverse genetics at single-cell resolution

Proteostasis governs differential temperature sensitivity across embryonic cell types

Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy

Single-cell transcriptomic profiling of the zebrafish inner ear reveals molecularly distinct hair cell and supporting cell subtypes

Single cell, whole embryo phenotyping of pleiotropic disorders of mammalian development

Nuclear oligo hashing improves differential analysis of single-cell RNA-seq

Transcriptomic profiling of tissue environments critical for post-embryonic patterning and morphogenesis of zebrafish skin

A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface

Dimensionality reduction by UMAP to visualize physical and genetic interactions

Inferring Causal Gene Regulatory Networks from Coupled Single-Cell Expression Dynamics Using Scribe

Massively multiplex chemical transcriptomics at single cell resolution

Thyroid hormone regulates distinct paths to maturation in pigment cell lineages

Dynamics of gene expression in single root cells of Arabidopsis thaliana